The process of treatment is the door of the room where the hyperbaric treatment will be held is closed. The pressure is increased which may cause some noise. The surrounding will start to get warmer and the patient will have the same feeling in the ear as in case of landing in an airplane. The ear feels fullness in hyperbaric oxygen therapy. The patient will be taught beforehand ways to avoid this uneasiness by popping the ears or clearing them. The patient needs to equalize the ears as soon the pressure in the room starts increasing. There will be an attendant who will assist in case of any problem. They will also search for the most suitable way that makes a particular patient comfortable. For some people swallowing is enough. In case the discomfort still persists one can ask the attendant to reduce the pressure and rate of compression. Due to the decreasing pressure in the room, there can be some weird noises but that is nothing unusual.

The required pressure is set, that is normally 2 ata and a mask is placed over the face of the patient to breathe in oxygen. This is carried out throughout the session timings. The pressure has to reach the prescribed level as mentioned by a physician. The actual treatment starts at that point. After the completion of the session one can sleep, rest, watch television or simply read a book. Some chambers are well equipped where patients can carry out the above-mentioned activities. The mask can be removed but done only if really necessary. In case of an emergency, the room can be decompressed as well. As soon as the session timing ends the attendant will lower the pressure slowly at a comfortable pace. The normal duration is 2 hours for a session and can be performed every day.